We also just had this same "421 Misdirected Request" error on all the sites we hosted after unattended-upgrades auto updated this morning. Rolling back to previous version resolved for now.
Checking the apache error logs per site we say the following: > [Thu Jul 17 06:45:16.091474 2025] [ssl:error] [pid 2051895:tid 139659384452800] [client X.X.X.X:0] AH02032: Hostname 000-default.site.com (default host as no SNI was provided) and hostname www.site.co.uk provided via HTTP have no compatible SSL setup Requests to each site (e.g. www.site.co.uk used as example above) apache would appear to be using the default site's SSL instead of their per site SSL. Ref the comment about plesk, we don't use plesk btw, no management app like that, we have apache2 installed directly on ubuntu 24.04. -- You received this bug notification because you are a member of Ubuntu Bugs, which is subscribed to Ubuntu. https://bugs.launchpad.net/bugs/2117112 Title: 421 Misdirected Request To manage notifications about this bug go to: https://bugs.launchpad.net/ubuntu/+source/apache2/+bug/2117112/+subscriptions -- ubuntu-bugs mailing list ubuntu-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/ubuntu-bugs