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Here's To Biology: Nature's Own Nanomachines Dr. Steve Block, Biology and 
Applied Physics
To study single molecules, Block has pioneered the use of optical tweezers, tiny laser-based "tractor beams" 
that produce miniscule piconewton forces to drag around molecules and allow measurements of displacements on the order 
of a nanometer. "You can stop and stall molecules, w follow their motion. Recently, we've studied the backtracking 
of RNA polymerase: when it makes a mistake, it can actually back up by five bases, scoop off the wrong thing and start 
again," says Block. While biological nanotechnology "hasn't even arrived at its infancy yet," says 
Block, "biological nanoscience is a very exciting place to be right now, because the techniques now exist to truly 
study proteins, and we're learning so much about them."
Currently, the gate length, the characteristic length parameter in transistors, 
has hit about 90 nm. The shorter the gate length, the faster transistors can 
switch on and off. In fact, the transistors have gotten so fast, that the delay 
as electrons flow through the skinnier and longer wires needed to cross larger, 
complex chips is on track to become the limiting factora in speed. This delay 
is just one of the fundamental problems that threatens to make the nanoscale 
regime of electronics unfaithful to Moore's Law and demands the design of new 
materials and structures or a complete shift in chip architecture.





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