Dear all, I have a loop truncation that could be explained as
ProteinName(1-20)-GSSGSS-(40-500), where residues 21-39 was replaced with a
GSSGSS linker. Now the problem is in Coot, how do I define this mutant in a
way that I could still preserve the numbering of the native residues while
allowing the loop to become an integral part of the continuous polypeptide
chain?

 A related question is then would Refmac handle such a model properly in
refinement?

Thank you in advance for your help, -yong

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