I've find a solution. I think is a Linux kernel problem with mouse's multiplexer.
I've added "i8042.nomux" to the booting kernel and the problem goes
away.
** Also affects: linux (upstream)
Importance: Undecided
Status: Unconfirmed
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When my laptop access acpi subsystem the mouse, sound, ecc.. stop working
https://launchpad.net/bugs/50188
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