As I stated in the comment, I downgraded the systemd packages to 3.11 to try to get to a working state, but the error persisted after the downgrade.
To get the full picture, these were the updated packages after which kvm stopped to work: root@MGL1-SRV-0006:~# apt list --upgradable Listing... Done libnss-mymachines/focal-updates 245.4-4ubuntu3.13 amd64 [upgradable from: 245.4-4ubuntu3.11] libnss-systemd/focal-updates 245.4-4ubuntu3.13 amd64 [upgradable from: 245.4-4ubuntu3.11] libpam-systemd/focal-updates 245.4-4ubuntu3.13 amd64 [upgradable from: 245.4-4ubuntu3.11] libsystemd0/focal-updates 245.4-4ubuntu3.13 amd64 [upgradable from: 245.4-4ubuntu3.11] libudev1/focal-updates 245.4-4ubuntu3.13 amd64 [upgradable from: 245.4-4ubuntu3.11] libudisks2-0/focal-updates 2.8.4-1ubuntu2 amd64 [upgradable from: 2.8.4-1ubuntu1] libvirt-clients/focal-updates 6.0.0-0ubuntu8.14 amd64 [upgradable from: 6.0.0-0ubuntu8.13] libvirt-daemon-driver-qemu/focal-updates 6.0.0-0ubuntu8.14 amd64 [upgradable from: 6.0.0-0ubuntu8.13] libvirt-daemon-driver-storage-rbd/focal-updates 6.0.0-0ubuntu8.14 amd64 [upgradable from: 6.0.0-0ubuntu8.13] libvirt-daemon-system-systemd/focal-updates 6.0.0-0ubuntu8.14 amd64 [upgradable from: 6.0.0-0ubuntu8.13] libvirt-daemon-system/focal-updates 6.0.0-0ubuntu8.14 amd64 [upgradable from: 6.0.0-0ubuntu8.13] libvirt-daemon/focal-updates 6.0.0-0ubuntu8.14 amd64 [upgradable from: 6.0.0-0ubuntu8.13] libvirt0/focal-updates 6.0.0-0ubuntu8.14 amd64 [upgradable from: 6.0.0-0ubuntu8.13] python3-os-vif/focal-updates 2.0.0-0ubuntu2 all [upgradable from: 2.0.0-0ubuntu1] python3-pyroute2/focal-updates 0.5.9-0ubuntu2 all [upgradable from: 0.5.9-0ubuntu1] systemd-container/focal-updates 245.4-4ubuntu3.13 amd64 [upgradable from: 245.4-4ubuntu3.11] systemd-sysv/focal-updates 245.4-4ubuntu3.13 amd64 [upgradable from: 245.4-4ubuntu3.11] systemd/focal-updates 245.4-4ubuntu3.13 amd64 [upgradable from: 245.4-4ubuntu3.11] udev/focal-updates 245.4-4ubuntu3.13 amd64 [upgradable from: 245.4-4ubuntu3.11] udisks2/focal-updates 2.8.4-1ubuntu2 amd64 [upgradable from: 2.8.4-1ubuntu1] -- You received this bug notification because you are a member of Ubuntu Bugs, which is subscribed to Ubuntu. https://bugs.launchpad.net/bugs/1943990 Title: After updating systemd packages to 245.4-4ubuntu3.13 and libvirt packages to 6.0.0-0ubuntu8.14, it is no longer possible to start kvm virtual machines To manage notifications about this bug go to: https://bugs.launchpad.net/ubuntu/+source/systemd/+bug/1943990/+subscriptions -- ubuntu-bugs mailing list ubuntu-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/ubuntu-bugs