I also have this problem. My solution has been to toggle the Terminal (Ctrl + Alt + F1) and then toggle bock to Gnome (Gtrl + Alt + F7)
Linux Orithyia 3.13.0-24-generic #47-Ubuntu SMP Fri May 2 23:30:00 UTC 2014 x86_64 x86_64 x86_64 GNU/Linux GNOME Shell 3.10.4 -- You received this bug notification because you are a member of Ubuntu Bugs, which is subscribed to Ubuntu. https://bugs.launchpad.net/bugs/1181666 Title: gnome-shell randomly blocks mouse from working To manage notifications about this bug go to: https://bugs.launchpad.net/gnome-shell/+bug/1181666/+subscriptions -- ubuntu-bugs mailing list ubuntu-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/ubuntu-bugs