1. Reboot the machine
2. Press ESC upon GRUB menu appeared
3. Press "e" to enter edit mode of GRUB command launching kernel
4. find line with kernel options - it should contain one or more words "quiet", 
"splash", "image"
6. fix cursor at the and of the line and enter "pci=routeirq" (w/o quotes)
7. press F10 to make GRUB go on.

If things will go well - add the option to GRUB_CMDLINE_LINUX as
described in my previous post

If thing will not go well, repeat the above procedure, but this time
enter the option "pci=nocrs" ( the newer motherboard/BIOS you have the
more likely you will require it).

Good luck!

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https://bugs.launchpad.net/bugs/1087519

Title:
  Serial port ttyS4 doesn't work in 12.04

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