I have a similar issue.  I'm running 12.04 on a ThinkPad T410s.  My USB
mouse behaved very erratically when docked, randomly moving across the
screen every few seconds and registering false clicks, rendering the
system useless. However I am able to duplicate the problem running
undocked when the laptop screen is closed.  When the screen is opened
(and disabled, since I'm using an external monitor) then my USB mouse
works fine.
Perhaps the issue is actually that the trackpad is not disabled when the
screen is closed?

Can others who are seeing problems with USB mice see if it still happens
when the laptop is open or only when closed?

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https://bugs.launchpad.net/bugs/994743

Title:
  After 11.10 > 12.04 upgrade on Thinkpad W520 - mouse input broken

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