Thanks for the bug report.
The sudo command gives you superuser privileges. Please try:
sudo dpkg --configure -a
Does this fix the problem?
** Changed in: update-manager (Ubuntu)
Assignee: (unassigned) => Tom Mortimer-Jones
Status: Unconfirmed => Needs Info
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E: _cache->open() failed
https://bugs.launchpad.net/bugs/119731
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