Same problem after 45 mins when using Toshiba Satellite L20 running Xubuntu 6.06 with Microsoft Optical Wheel Mouse luckily onboard touchpad still works !
Unplug mouse and it disappears from "lsusb" replug and "lsusb" then hangs as well ! -- pmouse.c loses sync, USB optical mouse becomes paperweight https://launchpad.net/bugs/66187 -- ubuntu-bugs mailing list ubuntu-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/ubuntu-bugs