Additionally to what's already been said, you may also want to have a look at the Pyjamas project (which can work in conjunction with Django as a back-end), there's a short article about implementing an MVC architecture in Pyjamas here: http://pyjs.org/wiki/modelviewcontroller/
Also you may want to have a look at the Python implementation of PureMVC (which as the previous page mentions can be used in conjuntion with Pyjamas as well): http://trac.puremvc.org/PureMVC_Python/ Walter
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