Yes I've used it with Unicode, see test_unicode in the unittests [1]. In fact one of the reasons why it was moved to google-code was so we could rapidly fix some of the outstanding problems with the python client. If you can demonstrate a bug using the unittests we've got for it that would be great.
//Ed [1] http://code.google.com/p/solrpy/source/browse/trunk/tests/test_all.py
