For every specific V1 and V4 pair (ex:A and P) calculate Linear regression of
V3(y-axis) and V2(x-axis)
and print p value along with the pair (output).

INPUT
#############
V1      V2      V3 V4
A       1       2.5     P
A       2       2.8     P
A       3       3.2     P
A       2       1.1     Q
A       3       1.7     Q
A       1       2.2     Q
B       1       2.5     P
B       2       2.9     P
B       3       3.0     P

SCRIPT
#######
data1<-read.table("INPUT", header=TRUE)
fm <- lmList(V3~V2|V1,V4 data=data1)
get.pval <- function(z) {
  x <- summary(z)
  pf(x$fstatistic[1L],
                x$fstatistic[2L], x$fstatistic[3L], lower.tail = FALSE)
}
sapply(fm,get.pval) 

OUTPUT
########
A       PVALUE[LINEAR REGRESSION]       P
A       P........................       Q
B       P........................       P
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