Sorry for being impatient but is there really no way of doing this at all?
It's quite urgent so any help is very much appreciated. Thank you.



RWilliam wrote:
> 
> Hello,
> 
> I just started using R to do epidemiologic simulation research using the
> Cox proportional hazard model. I have 2 covariates X1 and X2 which I want
> to model as h(t,X)=h0(t)*exp(b1*X1+b2*X2). I assume independence of X from
> t. 
> 
> After I simulate Time and Censor data vectors denoting the censoring time
> and status respectively, I can call the following function to fit the data
> into the Cox model (a is a data.frame containing 4 columns X1, X2, Time
> and Censor):
> b = coxph (Surv (Time, Censor) ~ X1 + X2, data = a, method = "breslow");
> 
> Now the purpose of me doing simulation is that I have another mechanism to
> generate the number b2. From the given b2 (say it's 4.3), Cox model can be
> fit to generate b1 and check how feasible the new model is. Thus, my
> question is, how do I specify such a model that is partially completed (as
> in b2 is known). I tried things like Surv(Time,Censor)~X1+4.3*X2, but it's
> not working. Thanks very much.
> 

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