After an extremely long gestation, a new version of the coxme package is
now available on CRAN. This function fits very general mixed-effects
Cox models using an lmer-like syntax. For instance here is a model that
fits a random treatment effect, using data from a multi-study
collaboration.
fit <- coxme(Surv(pg.time, pg.stat) ~ stage + trt + (trt|site) +
stata(site), data= multicolon)
The program allows for multiple random effects, and differing variance
structures for them. It currently has a fairly simple vignette showing
how to use the package; I'll be improving this to include more examples
over the next few months.
Terry Therneau
Mayo Clinic
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