Kaliss wrote:
Hi list,


I'm new to R and I'm currently using ROCR package.
Data in input look like this:

DIAGNOSIS       SCORE
1       0.387945
1       0.50405
1       0.435667
1       0.358057
1       0.583512
1       0.387945
1       0.531795
1       0.527148
0       0.526397
0       0.372935
1       0.861097

And I run the following simple code:
d <- read.table("inputFile", header=TRUE);
pred <- prediction(d$SCORE, d$DIAGNOSIS);
perf <- performance( pred, "tpr", "fpr");
plot(perf)

So building the curve works easily.
My question is: can I have the specificity and the sensitivity for
a score threshold = 0.5 (for example)? How do I compute this ?
Thank you in advance

Beware of the utility/loss function you are implicitly assuming with this approach. It is quite oversimplified. In clinical practice the cost of a false positive or false negative (which comes from a cost function and the simple forward probability of a positive diagnosis, e.g., from a basic logistic regression model if you start with a cohort study) vary with the type of patient being diagnosed.

Frank

--
Frank E Harrell Jr   Professor and Chair           School of Medicine
                     Department of Biostatistics   Vanderbilt University

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