Hi,

I have not followed this thread from the beginning, but have you tried the foverlaps() function from the data.table package?

Something along the lines of:

---
# create the tables (use as.data.table() or setDT() if you
# start with a data.frame)
mapfile <- data.table(Name = c("S1", "S2", "S3"), Chr = 1,
                      Position = c(3000, 6000, 1000))
Chr.Arms <- data.table(Chr = 1, Arm = c("p", "q"),
                       Start = c(0, 5001), End = c(5000, 10000))

# add a dummy variable to be able to define Position as an interval
mapfile[, Position2 := Position]

# add keys
setkey(mapfile, Chr, Position, Position2)
setkey(Chr.Arms, Chr, Start, End)

# use data.table::foverlaps (see ?foverlaps)
mapfile <- foverlaps(mapfile, Chr.Arms, type = "within")

# remove the dummy variable
mapfile[, Position2 := NULL]

# recreate original order
setorder(mapfile, Chr, Name)

---

BTW, there is a typo in your *SOLUTION*. I guess you wanted to write data.table(Name = c("S1", "S2", "S3"), Chr = 1, Position = c(3000, 6000, 1000), key = "Chr") instead of data.frame(Name = c("S1", "S2", "S3"), Chr = 1, Position = c(3000, 6000, 1000), key = "Chr").

HTH,
  Denes



On 01/30/2016 07:48 PM, Gaius Augustus wrote:
I'll look into the Intervals idea.  The data.table code posted might not
work (because I don't believe it would put the rows in the correct order if
the chromosomes are interspersed), however, it did make me think about
possibly assigning based on values...

*SOLUTION*
mapfile <- data.frame(Name = c("S1", "S2", "S3"), Chr = 1, Position =
c(3000, 6000, 1000), key = "Chr")
Chr.Arms <- data.frame(Chr = 1, Arm = c("p", "q"), Start = c(0, 5001), End
= c(5000, 10000), key = "Chr")

for(i in 1:nrow(Chr.Arms)){
   cur.row <- Chr.Arms[i, ]
   mapfile$Arm[ mapfile$Chr == cur.row$Chr & mapfile$Position >=
cur.row$Start & mapfile$Position <= cur.row$End] <- cur.row$Arm
}

This took out the need for the intermediate table/vector.  This worked for
me, and was VERY fast.  Took <5 minutes on a dataframe with 35 million rows.

Thanks for the help,
Gaius

On Sat, Jan 30, 2016 at 10:50 AM, Gaius Augustus <gaiusjaugus...@gmail.com>
wrote:

I'll look into the Intervals idea.  The data.table code posted might not
work (because I don't believe it would put the rows in the correct order if
the chromosomes are interspersed), however, it did make me think about
possibly assigning based on values...

Something like:
mapfile <- data.table(Name = c("S1", "S2", "S3"), Chr = 1, Position =
c(3000, 6000, 1000), key = "Chr")
Chr.Arms <- data.table(Chr = 1, Arm = c("p", "q"), Start = c(0, 5001), End
= c(5000, 10000), key = "Chr")

for(i in 1:nrow(Chr.Arms)){
   cur.row <- Chr.Arms[i, ]
   mapfile[ Chr == cur.row$Chr & Position >= cur.row$Start & Position <=
cur.row$End] <- Chr.Arms$Arm
}

This might take out the need for the intermediate table/vector.  Not sure
yet if it'll work, but we'll see.  I'm interested to know if anyone else
has any ideas, too.

Thanks,
Gaius

On Fri, Jan 29, 2016 at 11:34 PM, Ulrik Stervbo <ulrik.ster...@gmail.com>
wrote:

Hi Gaius,

Could you use data.table and loop over the small Chr.arms?

library(data.table)
mapfile <- data.table(Name = c("S1", "S2", "S3"), Chr = 1, Position =
c(3000, 6000, 1000), key = "Chr")
Chr.Arms <- data.table(Chr = 1, Arm = c("p", "q"), Start = c(0, 5001),
End = c(5000, 10000), key = "Chr")

Arms <- data.table()
for(i in 1:nrow(Chr.Arms)){
   cur.row <- Chr.Arms[i, ]
   Arm <- mapfile[ Position >= cur.row$Start & Position <= cur.row$End]
   Arm <- Arm[ , Arm:=cur.row$Arm][]
   Arms <- rbind(Arms, Arm)
}

# Or use plyr to loop over each possible arm
library(plyr)
Arms <- ddply(Chr.Arms, .variables = "Arm", function(cur.row, mapfile){
   mapfile <- mapfile[ Position >= cur.row$Start & Position <= cur.row$End]
   mapfile <- mapfile[ , Arm:=cur.row$Arm][]
   return(mapfile)
}, mapfile = mapfile)

I have just started to use the data.table and I have the feeling the code
above can be greatly improved - maybe the loop can be dropped entirely?

Hope this helps
Ulrik

On Sat, 30 Jan 2016 at 03:29 Gaius Augustus <gaiusjaugus...@gmail.com>
wrote:

I have two dataframes. One has chromosome arm information, and the other
has SNP position information. I am trying to assign each SNP an arm
identity.  I'd like to create this new column based on comparing it to
the
reference file.

*1) Mapfile (has millions of rows)*

Name    Chr   Position
S1      1      3000
S2      1      6000
S3      1      1000

*2) Chr.Arms   file (has 39 rows)*

Chr    Arm    Start   End
1      p      0       5000
1      q      5001    10000


*R Script that works, but slow:*
Arms  <- c()
for (line in 1:nrow(Mapfile)){
       Arms[line] <- Chr.Arms$Arm[ Mapfile$Chr[line] == Chr.Arms$Chr &
  Mapfile$Position[line] > Chr.Arms$Start &  Mapfile$Position[line] <
Chr.Arms$End]}
}
Mapfile$Arm <- Arms


*Output Table:*

Name   Chr   Position   Arm
S1      1     3000      p
S2      1     6000      q
S3      1     1000      p


In words: I want each line to look up the location ( 1) find the right
Chr,
2) find the line where the START < POSITION < END), then get the ARM
information and place it in a new column.

This R script works, but surely there is a more time/processing efficient
way to do it.

Thanks in advance for any help,
Gaius

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