LW1949 1.0.0 is now available on CRAN.
LW1949 automates the steps taken in Litchfield and Wilcoxon’s (1949) manual
approach to evaluating dose-effect experiments. Letting the computer do the
work saves time and yields the best fit possible using the Litchfield
Wilcoxon approach (by minimizing the chi-squared statistic).
A brief demonstration of LW1949 is given in this web app,
https://jvadams.shinyapps.io/LW1949demo
An example of how to use the functions in LW1949 is given in this vignette,
https://rawgit.com/JVAdams/LW1949/master/vignettes/Intro.html
Litchfield, JT Jr. and F Wilcoxon. 1949. A simplified method of evaluating
dose-effect experiments. Journal of Pharmacology and Experimental
Therapeutics 96(2):99-113.
http://jpet.aspetjournals.org/content/96/2/99.abstract
Jean
`·.,, ><(((º> `·.,, ><(((º> `·.,, ><(((º>
Jean V. Adams
Statistician
U.S. Geological Survey
Great Lakes Science Center
223 East Steinfest Road
Antigo, WI 54409 USA
http://www.glsc.usgs.gov
http://profile.usgs.gov/jvadams
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