Hello,
�
I am a R-beginner and I need some help.�The question is very simple: I need to
do a pearson correlations (r,p-value and FDR with BH) from an Expression array
(with several thousand genes for lets say 20 cell lines)�with some features of
those cell lines.
My problem I have is the organization of the excel sheets and how to introduce
the data into R and run the script. I though the easiest and more organized for
me would be two expcel sheets:
1- Only Expression data (in rows the�genes and in colums cell lines)
2- Only the features (In row the features (e.g. a) growth rate, b) sensitivity
to some drugs) and in columns the cell lines).
-->That would creat both sheets with 20 colums.
Now I would like to get a correlation of the gene 1: the expression of all
lines with the growth rate.
the same for gene2... and soforth. I sould obtain as many r,p and BH(FDR) as
genes there are.
the same I would need to do for the sensitivity... and so on.
Do you think this is doable? I am not at all a bioinformatic expert, so all
help is very welcome.
Thank you very much!
Kind regards,
Sarah
--
Sarah Bazzocco, PhD student
Group of Molecular Oncology,
CIBBIM-Nanomedicine,
Vall d'Hebron Hospital Research Institute,
Passeig Vall d'Hebron 119-129,
Barcelona 08035, Spain.
Tel: +34-93-489-4056
Fax: +34-93-489-3893
Email: sarah.bazzo...@vhir.org
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