Good Morning, 

I am not asking for a method by how to implement, if possible, the method in R. 
I am pretty confident of my statistical approach, I do not want to do it by 
hand :-). Although, I do have the formulas to do it by hand. The groups are 
measured once. The animal is treated short or long term unilaterally and not at 
all on the contralateral side. Each animal provides a no tx and tx value taken 
at the same end point. The external controls have had neither side treated. I 
have included a sample data table below: 

        Treatment 
        Duration        No Tx   TX 
        acute   7       9 
        acute   5       8 
        acute   4       7 
        3 weeks         21      23 
        3 weeks         28      27 
        3 weeks         26      29 
                        
                No Tx   No Tx 
        Control         3       2 
        Control         4       5 
        Control         7       9 

Thanks for your continued help. 
----- Original Message -----

> From: "c06n [via R]" <ml-node+s789695n470618...@n4.nabble.com>
> To: "Darcy Trimpe" <darcy.m.tri...@wmich.edu>
> Sent: Tuesday, April 21, 2015 1:36:28 AM
> Subject: Re: Two Factorial Experiment with a Single Control Group

> Hi,

> I'm not 100% sure I understand your approach. Right now it sounds
> more of a methods question than a R question.

> Here's what I understood so far:
> 1. you have 3 groups: no treatment at all, acute treatment, treatment
> over 3 weeks.
> 2. you measure those 3 groups: initially, after 3 weeks.

> That sounds to me that you have only 1 factor with 3 levels, and
> measure your dependent variable twice. This would yield a typical
> one factorial within-design.

> But I somehow feel that is not really your design. Can you provide an
> example table for the factor combinations with example data (can be
> made up)?

> If you reply to this email, your message will be added to the
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> NAML




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