Hi Ashish,

I am rather more concerned about whether what you outlined is legitimate (your question 1 below). If you are looking at children, higher AGE will be associated with higher TIV, so both variables would essentially measure the same thing (see Miller & Chapman, Misunderstanding Analysis of Covariance), which I really would not like to see.

Of course, if you are looking at adults, this will probably not apply.

Best wishes,
Stephan


Ashish Ranpura schrieb:

Dear all,

I'm attempting to plot a cubic relationship between two variables controlling for the effects of a third variable. In this short example, I'm trying to use AGE to predict CORTEX while controlling for the effects of TIV (total intracranial volume):

(snip)

Although the last 'lines' command fails, summary(cortex.lm) does give me reasonable coefficients for the multiple regression. Can anyone advise me if (1) this is at all a legitimate procedure, and (2) how to draw the cubic function that fits the multiple regression?

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