Dear Dr. Therneau, 
Thanks a lot for your answer. I use your survival package often and I find it 
very useful.

Cheers, 
Oscar

Oscar M. Rueda, PhD.
 Postdoctoral Research Fellow, Caldas Lab, Breast Cancer Functional
 Genomics.
 University of Cambridge. Cancer Research UK Cambridge Institute.
 Li Ka Shing Centre, Robinson Way.
 Cambridge CB2 0RE
 England
________________________________________
From: Therneau, Terry M., Ph.D. [thern...@mayo.edu]
Sent: Wednesday, January 29, 2014 2:35 PM
To: Oscar Rueda; r-help@r-project.org
Subject: Re:  [R] anova.coxph with subsets of data

--- begin included message ---


But If I do

> fit <- coxph(Surv(futime, fustat) ~ resid.ds *rx + ecog.ps, data = ovarian, 
> subset=ovarian$age>50)
>  anova(fit)
>  fit2 <- coxph(Surv(futime, fustat) ~ resid.ds +rx + ecog.ps, data=ovarian, 
> subset=ovarian$age>50)
>  anova(fit2,fit)

The first p-value seems to be wrong.
Would anybody please explain to me why?

Cheers,
Oscar

---- end inclusion ----

The p-value seems wrong because it is wrong.  You've found a bug in the 
survival package.
(It has to do with missing values, and the attempt of anova.coxph to ensure 
that it does
not fit a sequence of models such that an observation is dropped partway 
through the list.)


Terry Therneau


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