Hi, this is a statistical question rather than a pure R question. I have got
many help from R mailing list in the past, so would like to try here and
appreciate any input:
I conducted Mantel-Haenszel test to show that the performance of a diagnostic
test did not show heterogeneity among 4 study sites, i.e. Mantel Haenszel test
p value > 0.05, so that I could conduct a meta-analysis by combining data of
all 4 study sites.
Now one of the reviewers for the manuscript did a powering analysis for Mantel
Haneszel test showing that with the sample sizes I have, the power for Mantel
Haeszel test was only 50%. So he argued that I did not have enough power for
Mantel Haenszel test.
My usage of Mantel Haenszel was NOT to show a significant p value, instead a
non-sginificant p value was what I was looking for because non-significant p
value indicate NO heterogeneity among study sites. Powering analysis in general
is to show whether you have enough sample size to ensure a statistical
significant difference can be seen with certain likelihood. But this is not how
I used Mantel Haenszel test. So I think in my scenario, the power analysis is
NOT applicable because I am simply using the test to demonstrate a
non-significant p value.
Am I correct on this view?
Thanks and appreciate any thoughts.
John
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