Your question has effectively nothing to do with R, so is off topic here. Post on a statistics or bioinformatics site like stats.stackexchange.com .
I'll just mention that this is a ubiquitous issue in, e.g. gene testing (p>>n), is controversial, philosophical, and complex. You may have a good bit of reading to do. -- Bert On Tue, Jul 23, 2013 at 7:50 AM, Jie <jimmycl...@gmail.com> wrote: > Dear All, > > I performed thousands of testings and obtained p-values. > And then I did two-sided uniform KS test of the p-values, the result > claimed it is uniform. > So does it mean that my model are wrong? Because I expect more small > p-values near 0. > This is a preliminary step before correcting the multiplicity. > Attached is hist of p-values (does this list allow attachment?). The ks test: > > One-sample Kolmogorov-Smirnov test > > D = 0.0493, p-value = 1.388e-06 > > alternative hypothesis: two-sided > > Thank you for your attention. > > Best wishes, > Jie > > ______________________________________________ > R-help@r-project.org mailing list > https://stat.ethz.ch/mailman/listinfo/r-help > PLEASE do read the posting guide http://www.R-project.org/posting-guide.html > and provide commented, minimal, self-contained, reproducible code. > -- Bert Gunter Genentech Nonclinical Biostatistics Internal Contact Info: Phone: 467-7374 Website: http://pharmadevelopment.roche.com/index/pdb/pdb-functional-groups/pdb-biostatistics/pdb-ncb-home.htm ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.
