Dear Frank Frank E Harrell Jr <[EMAIL PROTECTED]> wrote:
A few observations. 1. With minimal overfitting, rcorr.cens(predict(fit), Y) gives a good standard error for Dxy = 2*(C-.5) and bootstrapping isn't very necessary 2. If you bootstrap use the nonparametric bootstrap percentile method or other methods that constrain the confidence interval to be in [0,1]. 3. I don't know why the model would be linear on the two predictors you are using.
Do you mean using these predictors fitted with spline functions?? I have read about it in your "Regression Modeling Strategies" but I am not very sure I understand the use of them. I will read through it again.
David
Frank -- Frank E Harrell Jr Professor and Chair School of Medicine Department of Biostatistics Vanderbilt University
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