Dear Frank

Frank E Harrell Jr <[EMAIL PROTECTED]> wrote:


A few observations.

1. With minimal overfitting, rcorr.cens(predict(fit), Y) gives a good
standard error for Dxy = 2*(C-.5) and bootstrapping isn't very necessary

2. If you bootstrap use the nonparametric bootstrap percentile method
or  other methods that constrain the confidence interval to be in [0,1].

3. I don't know why the model would be linear on the two predictors you
are using.

Do you mean using these predictors fitted with spline functions?? I have read about it in your "Regression Modeling Strategies" but I am not very sure I understand the use of them. I will read through it again.

David


Frank

--
Frank E Harrell Jr   Professor and Chair           School of Medicine
                     Department of Biostatistics   Vanderbilt University

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