Hi Albyn,

Not a problem :)

I had calculated the CI using

>confint(Regression_PhyloContrasts, level=0.95)

Is that adequate? I had been using this as my indicator of significance,
but ultimately I need a P-value for the deviation from a slope of 1. Which
is where I ran into trouble trying to use offset( ) to change the default
assumption of the linear model.

Cat




On Sat, Nov 24, 2012 at 11:52 PM, Albyn Jones <jo...@reed.edu> wrote:

> Dear Cat
>
> My apologies for presuming...
>
> Here's a "primitive" solution:  compute a t-statistic or CI.
>
> t = (beta-hat - 1)/SE(beta-hat), compare to qt(.975, res.df)
>
> Or Better, compute the 95% confidence interval
>
>   beta-hat + c(-1,1)*qt(.975, res.df)*SE(beta-hat)
>
> albyn
>
>
> On 2012-11-24 18:05, Catriona Hendry wrote:
>
>> Hi,
>>
>> @ Albyn, David.. No, its not homework. Its basic groundwork for testing
>> allometric relationships for a graduate project I am working on. I read
>> the
>> guide before posting, I spent half the day trying to understand how I am
>> going wrong based on the advice given to others.
>>
>> @Bert, David... I apologise for the lack of code, I wasn't sure how to
>> explain my problem and I guess I went about it the wrong way.
>>
>> I do think this is what I need to be doing, I am testing allometric
>> relationships of body size against a predicted isometric (1:1)
>> relationship. So I would like to know if the relationship between my
>> variables deviates from that.
>>
>> Hopefully the information below will be what is needed.
>>
>> Here is the part of the code relevant to the regression and plot:
>>
>>
>>  plot(Contrast_log_MTL_ALL, Contrast_log_FTL_ALL)
>>>
>>
>>  Regression_PhyloContrasts_ALL <- lm(Contrast_log_FTL_ALL ~
>>>
>> Contrast_log_MTL_ALL, offset=1*Contrast_log_MTL_ALL)
>> abline(Regression_**PhyloContrasts_ALL)
>>
>> the plot that resulted is attached as an image file.
>>
>>
>> Below are the vectors of my variables. The are converted from other values
>> imported and indexed from a csv file, so unfortunately I don't have matrix
>> set up for them.
>>
>>   Contrast_log_FTL_ALL Contrast_Log_MTL_ALL  83 0.226593 0.284521  84
>> 0.165517 0.084462  85 -0.1902 -0.0055  86 0.585176 0.639916  87 -0.01078
>> 0.118011  88 0.161142 0.073762  89 -0.08566 -0.04788  90 -0.13818 -0.0524
>> 91 -0.02504 -0.21099  92 -0.05027 -0.07594  93 -0.11399 -0.07251  94
>> -0.07299 -0.08247  95 -0.09507 -0.04817  96 0.207591 0.151695  97 -0.14224
>> -0.05097  98 0.06375 -0.0229  99 0.04607 0.06246  100 0.257389 0.190531
>>  101
>> -0.0612 -0.10902  102 -0.1981 -0.24698  103 -0.12328 -0.36942  104
>> 0.269877
>> 0.341989  105 0.125377 0.227183  106 0.087038 -0.05962  107 0.114929
>> 0.096112  108 0.252807 0.305583  109 -0.0895 -0.08586  110 -0.38483
>> -0.20671
>> 111 -0.72506 -0.63785  112 -0.37212 -0.21458  113 0.010348 0.117577  114
>> -0.09625 -0.0059  115 -0.26291 -0.25986  116 0.056922 0.064041  117
>> 0.051472
>> -0.09747  118 -0.05691 0.075005  119 0.117095 -0.15497  120 -0.01329
>> -0.12473  121 0.098725 0.020522  122 -0.0019 -0.01998  123 -0.12446
>> -0.02312
>> 124 0.019234 0.031391  125 0.385366 0.391766  126 0.495518 0.468946  127
>> -0.09251 -0.08045  128 0.147965 0.139117  129 -0.03143 -0.02319  130
>> -0.19801 -0.14924  131 0.014104 -0.01917  132 0.031872 -0.01381  133
>> -0.01412 -0.04381  134 -0.12864 -0.08527  135 -0.07179 -0.03525  136
>> 0.31003
>> 0.29553  137 -0.09347 -0.11903  138 -0.10706 -0.16654  139 0.078655
>> 0.065509
>> 140 0.08279 -0.00766  141 0.181885 0.001414  142 0.345818 0.496323  143
>> 0.235044 0.095073  144 -0.03022 0.039918  145 0.042577 0.136586  146
>> 0.064208 0.001379  147 -0.02237 -0.03009  148 -3.55E-05 0.040197  149
>> 0.011168 0.087116  150 0.019964 0.071822  151 -0.04602 -0.06616  152
>> 0.083087 0.038592  153 0.032078 0.107237  154 -0.21108 -0.22347  155
>> 0.122959 0.297917  156 -0.05898 0.012547  157 -0.07584 -0.21588  158
>> -0.00929 -0.06864  159 -0.01211 -0.04559  160 0.090948 0.136582  161
>> 0.016974 0.018259  162 -0.04083 0.016245  163 -0.20328 -0.31678
>>
>>
>>
>>
>>
>>
>> On Sat, Nov 24, 2012 at 8:22 PM, Bert Gunter <gunter.ber...@gene.com>
>> wrote:
>>
>>  1. The model is correct :  lm( y~ x + offset(x))
>>> ( AFAICS)
>>>
>>> 2. Read the posting guide, please: Code? I do not know what you mean by:
>>>
>>> " this resulted in a regression line that was plotted perpendicular to
>>> the data when added with the abline function."
>>>
>>> Of course, maybe someone else will groc this.
>>>
>>> 3. I wonder if you really want to do what you are doing, anyway. For
>>> example, in comparing two assays to see whether they give "similar"
>>> results, you would **not** do what you are doing. If you care to follow
>>> up
>>> on this, I suggest you post complete context to a statistical mailing
>>> list,
>>> not here, like stats.stackexchange .com.  Also, feel free to ignore me,
>>> of
>>> course. I'm just guessing.
>>>
>>> Cheers,
>>> Bert
>>>
>>> Cheers,
>>> Bert
>>>
>>>
>>> On Sat, Nov 24, 2012 at 4:27 PM, Catriona Hendry <hen...@gwmail.gwu.edu
>>> >wrote:
>>>
>>>  Hi!
>>>>
>>>> I have a question that is probably very basic, but I cannot figure out
>>>> how
>>>> to do it. I simply need to compare the significance of a regression
>>>> slope
>>>> against a slope of 1, instead of the default of zero.
>>>>
>>>> I know this topic has been posted before, and I have tried to use the
>>>> advice given to others to fix my problem. I tried the offset command
>>>> based
>>>> on one of these advice threads as follows:
>>>>
>>>> Regression <- lm(y~x+offset(1*x))
>>>>
>>>> but this resulted in a regression line that was plotted perpendicular to
>>>> the data when added with the abline function.
>>>>
>>>> I would be extremely grateful for your help!!
>>>>
>>>> Thanks!!
>>>>
>>>> Cat
>>>>
>>>>         [[alternative HTML version deleted]]
>>>>
>>>> ______________________________**________________
>>>> R-help@r-project.org mailing list
>>>> https://stat.ethz.ch/mailman/**listinfo/r-help<https://stat.ethz.ch/mailman/listinfo/r-help>
>>>> PLEASE do read the posting guide
>>>> http://www.R-project.org/**posting-guide.html<http://www.R-project.org/posting-guide.html>
>>>> and provide commented, minimal, self-contained, reproducible code.
>>>>
>>>>
>>>
>>>
>>> --
>>>
>>> Bert Gunter
>>> Genentech Nonclinical Biostatistics
>>>
>>> Internal Contact Info:
>>> Phone: 467-7374
>>> Website:
>>>
>>>
>>> http://pharmadevelopment.**roche.com/index/pdb/pdb-**
>>> functional-groups/pdb-**biostatistics/pdb-ncb-home.htm<http://pharmadevelopment.roche.com/index/pdb/pdb-functional-groups/pdb-biostatistics/pdb-ncb-home.htm>
>>>
>>>
>>>
>>>
> ______________________________**________________
> R-help@r-project.org mailing list
> https://stat.ethz.ch/mailman/**listinfo/r-help<https://stat.ethz.ch/mailman/listinfo/r-help>
> PLEASE do read the posting guide http://www.R-project.org/**
> posting-guide.html <http://www.R-project.org/posting-guide.html>
> and provide commented, minimal, self-contained, reproducible code.
>



-- 
-----------------------------------------
*Catriona Hendry*
*Postgraduate Student*
*Biological Sciences Department*
*George Washington University*
*hen...@gwmail.gwu.edu*

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