My guess: You probably are overfitting your data. A straight line does about as well as anything except for the 3 high leverage points, which the minimization is probably having trouble with.
-- Bert On Thu, Sep 27, 2012 at 10:43 AM, Benedikt Gehr <benedikt.g...@ieu.uzh.ch> wrote: > quantiles<-c(seq(.05,.95,0.05)) > slopes<-c( 0.000000e+00, 1.622074e-04 , 3.103918e-03 , 2.169135e-03 , > 9.585523e-04 > ,1.412327e-03 , 4.288103e-05, -1.351171e-04 , 2.885810e-04 ,-4.574773e-04 > , -2.368968e-03, -3.104634e-03, -5.833970e-03, -6.011945e-03, -7.737697e-03 > , -8.203058e-03, -7.809603e-03, -6.623985e-03, -9.414477e-03) > plot(slopes~quantiles) -- Bert Gunter Genentech Nonclinical Biostatistics Internal Contact Info: Phone: 467-7374 Website: http://pharmadevelopment.roche.com/index/pdb/pdb-functional-groups/pdb-biostatistics/pdb-ncb-home.htm ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.