Hi, Here is the summary-output of the Coxph-model I used (the output is based on the best final model i.e. all significant explanatory variables and their interactions are included):
coxph(formula = Y ~ LT + Food + Temp2 + LT:Food + LT:Temp2 + Food:Temp2 + LT:Food:Temp2) n= 555 coef exp(coef) se(coef) z Pr(>|z|) LT 9.302e+02 Inf 2.822e+02 3.297 0.000979 *** Food 3.397e+03 Inf 1.023e+03 3.321 0.000896 *** Temp2 5.016e+03 Inf 1.522e+03 3.296 0.000979 *** LT:Food -2.250e+02 1.950e-98 6.807e+01 -3.305 0.000949 *** LT:Temp2 -3.327e+02 3.352e-145 1.013e+02 -3.284 0.001022 ** Food:Temp2 -1.212e+03 0.000e+00 3.666e+02 -3.307 0.000942 *** LT:Food:Temp2 8.046e+01 8.815e+34 2.442e+01 3.295 0.000986 *** --- Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 Rsquare= 0.123 (max possible= 0.858 ) Likelihood ratio test= 72.91 on 7 df, p=3.811e-13 Wald test = 55.79 on 7 df, p=1.042e-09 Score (logrank) test = 78.57 on 7 df, p=2.687e-14 Question is: How to interpret coefficient and exp(coef) values in this case, as they are very large values? Also 3-case interaction is involved, which confuses the interpretation more. All the examples concerning Coxph-model I have found so far online have been really simple regarding the intercation terms (which have always turned out to be unsignificant) and also coefficient-values (=hazard rates) and exponentials of these (=hazard ratios) have been pretty small and "easy to handle" numbers, e.g. coefficient = 1.73 -> exp(coef) = 5.64. BUT mine are way bigger numbers as you can see from the summary output (above). And because they are so large vaues, they almost seem to not make any sense. Grateful for the help, R-girl -- View this message in context: http://r.789695.n4.nabble.com/Cox-proportional-hazard-model-and-coefficients-tp4636366.html Sent from the R help mailing list archive at Nabble.com. ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.