Dear John,
Thank you very much for your help! It was very important for getting
along further.
I found out some additional things which I want to give back to you as
feedback (maybe other persons will have the same problems).
It's also possible to leave away the individual=T argument.
Instead you can use:
newdata.1<-
data.frame(unique(Rossi.2[c("start","stop")]),fin=0,age=30,prio=5,Id=1,arrest.time=0)
fit <- survfit(mod.allison.5, newdata.1, id=Id) *but not* fit <-
survfit(mod.allison.5, newdata.1, id="Id")
so you have to leave away the "" in specifying the id variable --> maybe
the help file could be more precise here.
Additionally I found out some more things while dealing with my original
data.
It's very important to specify the Surv object and the formula directly
in the coxph function, *so don't do this:*
SurvO <- Surv(Rossi.2$start, Rossi.2$stop, Rossi.2$arrest.time)
form <- as.formula(SurvO ~ fin + age + age:stop + prio)
mod.allison.5<- coxph(form,
data=Rossi.2)
mod.allison.5
newdata.1<-
data.frame(unique(Rossi.2[c("start","stop")]),fin=0,age=30,prio=5,arrest.time=0)
fit <- survfit(mod.allison.5, newdata.1, individual=T)
> Fehler in model.frame.default(data = newdata.1, formula = SurvO ~ fin
+ :
Variablenlängen sind unterschiedlich (gefunden für 'fin')
--> Error, length of variables are different
I think the error message is not optimal here, anyway.
The problem obviously consists in the survfit-function not recognizing
the names of the variables anymore.
It seems completely logic, but anyway, it took me many hours.
Thanks again,
Jürgen
--------- Korrespondenz ----------
Betreff: Re: How to specify "newdata" in a Cox-Modell with a time
dependent interaction term?
Von: John Fox <j...@mcmaster.ca>
An: J?rgen Biedermann <juergen.biederm...@googlemail.com>
Datum: 16.06.2012 17:22
> Dear Jurgen,
>
>> fit<- survfit(mod.allison.5, newdata.1, individual=TRUE)
>> fit
> Call: survfit(formula = mod.allison.5, newdata = newdata.1, individual = TRUE)
>
> records n.max n.start events median 0.95LCL 0.95UCL
> 19809 432 432 114 NA NA NA
>
> plot(fit) # shows one survival curve
>
> See ?survfit.coxph.
>
> Best,
> John
>
>
> On Sat, 16 Jun 2012 16:23:41 +0200
> Jürgen Biedermann<juergen.biederm...@googlemail.com> wrote:
>> Dear John,
>>
>> Thank you very much for the quick answer. I will use the mentioned citation
>> of your book in the future.
>>
>> However:
>> The Id argument is necessary for the function to know that the different
>> rows belong to one individual.
>>
>> Or how the Help-File says:
>>
>> id:
>> optional variable name of subject identifiers. If this is present, then each
>> group
>> of rows with the same subject id represents the covariate path through time
>> of
>> a single subject, and the result will contain one curve per subject. If the
>> coxph
>> fit had strata then that must also be specified in newdata. If missing, then
>> each
>> individual row of newdata is presumed to represent a distinct subject and
>> there
>> will be nrow(newdata) times the number of strata curves in the result (one
>> for
>> each strata/subject combination).
>>
>> I tried your proposal anyway, but, as expected, fifty different survival
>> curves appeared.
>>
>> So, there is still no solution.
>>
>> Best regards
>> Jürgen
>>
>> --
>> -----------------------------------
>> Jürgen Biedermann
>> Bergmannstraße 3
>> 10961 Berlin-Kreuzberg
>> Mobil: +49 176 247 54 354
>> Home: +49 30 940 53 044
>> e-mail: juergen.biederm...@gmail.com
>>
>>
>> --------- Korrespondenz ----------
>>
>> Betreff: Re: How to specify "newdata" in a Cox-Modell with a time dependent
>> interaction term?
>> Von: John Fox<j...@mcmaster.ca>
>> An: J?rgen Biedermann<juergen.biederm...@googlemail.com>
>> Datum: 16.06.2012 15:55
>>> Dear Jürgen,
>>>
>>> All the values of your Id variable are equal to 1; how can that make sense?
>>> Removing the argument Id=id may get you what you want.
>>>
>>> By the way, the document to which you refer was an appendix to a 2002 book
>>> that has been superseded by Fox and Weisberg, An R Companion to Applied
>>> Regression, Second Edition (Sage, 2011). Appendices for that book are
>>> available
>>> at<http://socserv.socsci.mcmaster.ca/jfox/Books/Companion/appendix.html>.
>>>
>>> I hope this helps,
>>> John
>>>
>>> ------------------------------------------------
>>> John Fox
>>> Sen. William McMaster Prof. of Social Statistics
>>> Department of Sociology
>>> McMaster University
>>> Hamilton, Ontario, Canada
>>> http://socserv.mcmaster.ca/jfox/
>>>
>>> On Sat, 16 Jun 2012 15:04:48 +0200
>>> Jürgen Biedermann<juergen.biederm...@googlemail.com> wrote:
>>>> Dear Mr. Therneau, Mr. Fox, or to whoever, who has some time...
>>>>
>>>> I don't find a solution to use the "survfit" function (package: survival)
>>>> for a defined pattern of covariates with a Cox-Model including a time
>>>> dependent interaction term. Somehow the definition of my "newdata"
>>>> argument seems to be erroneous.
>>>> I already googled the problem, found many persons having the same or a
>>>> similar problem, but still no solution.
>>>> I want to stress that my time-dependent covariate does not depend on the
>>>> failure of an individual (in this case it doesn't seem sensible to predict
>>>> a survivor function for an individual). Rather one of my effects declines
>>>> with time (time-dependent coefficient).
>>>>
>>>> For illustration, I use the example of John Fox's paper "Cox Proportional
>>>> - Hazards Regression for Survival Data".
>>>> http://cran.r-project.org/doc/contrib/Fox-Companion/appendix-cox-regression.pdf
>>>>
>>>> Do you know any help? See code below
>>>>
>>>> Thanks very much in advance
>>>> Jürgen Biedermann
>>>>
>>>> #----------------------------------------
>>>> #Code
>>>>
>>>> Rossi<-
>>>> read.table("http://cran.r-project.org/doc/contrib/Fox-Companion/Rossi.txt";,
>>>> header=T)
>>>>
>>>> Rossi.2<- fold(Rossi, time='week',
>>>> event='arrest', cov=11:62, cov.names='employed')
>>>>
>>>> # see below for the fold function from John Fox
>>>>
>>>> # modeling an interaction with time (Page 14)
>>>>
>>>> mod.allison.5<- coxph(Surv(start, stop, arrest.time) ~
>>>> fin + age + age:stop + prio,
>>>> data=Rossi.2)
>>>> mod.allison.5
>>>>
>>>> # Attempt to get the survivor function of a person with age=30, fin=0 and
>>>> prio=5
>>>>
>>>> newdata.1<-
>>>> data.frame(unique(Rossi.2[c("start","stop")]),fin=0,age=30,prio=5,Id=1,arrest.time=0)
>>>> fit<- survfit(mod.allison.5,newdata.1,id="Id")
>>>>
>>>> Error message:
>>>>
>>>> >Fehler in model.frame.default(data = newdata.1, id = "Id", formula =
>>>> Surv(start, :
>>>> Variablenlängen sind unterschiedlich (gefunden für '(id)')
>>>>
>>>> --> failure, length of variables are different.
>>>>
>>>> #-----------------------------------------------------------------
>>>> fold<- function(data, time, event, cov,
>>>> cov.names=paste('covariate', '.', 1:ncovs, sep=""),
>>>> suffix='.time', cov.times=0:ncov, common.times=TRUE, lag=0){
>>>> vlag<- function(x, lag) c(rep(NA, lag), x[1:(length(x)-lag)])
>>>> xlag<- function(x, lag) apply(as.matrix(x), 2, vlag, lag=lag)
>>>> all.cov<- unlist(cov)
>>>> if (!is.list(cov)) cov<- list(cov)
>>>> ncovs<- length(cov)
>>>> nrow<- nrow(data)
>>>> ncol<- ncol(data)
>>>> ncov<- length(cov[[1]])
>>>> nobs<- nrow*ncov
>>>> if (length(unique(c(sapply(cov, length), length(cov.times)-1)))>
>>>> 1)
>>>> stop(paste(
>>>> "all elements of cov must be of the same length and \n",
>>>> "cov.times must have one more entry than each element of
>>>> cov."))
>>>> var.names<- names(data)
>>>> subjects<- rownames(data)
>>>> omit.cols<- if (!common.times) c(all.cov, cov.times) else all.cov
>>>> keep.cols<- (1:ncol)[-omit.cols]
>>>> nkeep<- length(keep.cols)
>>>> if (is.numeric(event)) event<- var.names[event]
>>>> times<- if (common.times) matrix(cov.times, nrow, ncov+1, byrow=T)
>>>> else data[, cov.times]
>>>> new.data<- matrix(Inf, nobs, 3 + ncovs + nkeep)
>>>> rownames<- rep("", nobs)
>>>> colnames(new.data)<- c('start', 'stop', paste(event, suffix,
>>>> sep=""),
>>>> var.names[-omit.cols], cov.names)
>>>> end.row<- 0
>>>> for (i in 1:nrow){
>>>> start.row<- end.row + 1
>>>> end.row<- end.row + ncov
>>>> start<- times[i, 1:ncov]
>>>> stop<- times[i, 2:(ncov+1)]
>>>> event.time<- ifelse (stop == data[i, time]& data[i, event] ==
>>>> 1, 1, 0)
>>>> keep<- matrix(unlist(data[i, -omit.cols]), ncov, nkeep, byrow=T)
>>>> select<- apply(matrix(!is.na(data[i, all.cov]), ncol=ncovs),
>>>> 1, all)
>>>> rows<- start.row:end.row
>>>> cov.mat<- xlag(matrix(unlist(data[i, all.cov]),
>>>> nrow=length(rows)), lag)
>>>> new.data[rows[select], ]<-
>>>> cbind(start, stop, event.time, keep, cov.mat)[select,]
>>>> rownames[rows]<- paste(subjects[i], '.', seq(along=rows),
>>>> sep="")
>>>> }
>>>> row.names(new.data)<- rownames
>>>> as.data.frame(new.data[new.data[, 1] != Inf&
>>>> apply(as.matrix(!is.na(new.data[, cov.names])), 1, all), ])
>>>> }
>>>> #-----------------------------------------------------------------
>>>>
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