Sorry I'm not sure that prob is suitable for my purposes(but i'm quite
newbie with R).
If I correctly understand prob allows to set a weight for each row in the
original dataset in order to include the rows on the basis of their
weights). ... I'm not sure to correctly understanding ;-)
In my case all the rows are equally important. I  need  "simply " that my
subset has in each column the same frequency of  1 that in the original
dataset
Thank you again
Guido

2012/6/14 R. Michael Weylandt <michael.weyla...@gmail.com>

> sample() takes a prob = argument which lets you supply weights, which
> need not sum to one so, if I understand you, you could just pass TRUEs
> and FALSEs for those rows you want. If I'm wrong about that last bit,
> I'm still pretty confident sample(prob = ) is the way to go.
>
> Best,
> Michael
>
> On Thu, Jun 14, 2012 at 6:02 AM, Guido Leoni <guido.le...@gmail.com>
> wrote:
> > Dear list I wish to extract from a population genotypized for 10 SNP a
> > subsample of the same population of size n with similar allele
> frequencies.
> > Essentially i have a matrix of 200 rows (df) like this
> > Name,Condition,rs1385699_X,rs6625163_X,rs962458_X,Rs4658627_1,
> > sample01,Case,1,1,1,-1
> > sample02,Control,1,1,1,1
> > sample06,Control,1,-1,1,0
> > sample10,Case,1,1,1,0
> > sample11,Control,1,1,1,1
> > sample24,Control,-1,-1,1,0
> > sample29,Control,1,-1,1,0
> > sample42,Case,-1,-1,1,0
> > sample64,Case,-1,1,1,0
> > ....
> > I'm interested to mantain in my subsample the same frequencies of those
> > observed for the 1 value in each column
> > I approached the problem with sample() function
> >
> > mysample<-df[sample(1:nrow(df),100,replace=F),]
> > Then I tested that  the frequencies of each allele in mysample are not
> > statistically different respect to the initial dataset by mean of
> prop.test
> > This seems to work but do you know if there is a package that can do the
> > same thing  allowing for example a more strict control?
> > Thank you very much
> > Guido
> >
> >        [[alternative HTML version deleted]]
> >
> > ______________________________________________
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> > https://stat.ethz.ch/mailman/listinfo/r-help
> > PLEASE do read the posting guide
> http://www.R-project.org/posting-guide.html
> > and provide commented, minimal, self-contained, reproducible code.
>



-- 
Guido Leoni
National Research Institute on Food and Nutrition
(I.N.R.A.N.)
via Ardeatina 546
00178 Rome
Italy

tel     + 39 06 51 49 41 (operator)
        + 39 06 51 49 4498 (direct)

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