I followed this case while it was ongoing.
It was a very interesting example of basic mistakes but also (for me) of journal politicking. Keith Baggerly and Kevin Coombes wrote a great paper - "DERIVING CHEMOSENSITIVITY FROM CELL LINES: FORENSIC BIOINFORMATICS AND REPRODUCIBLE RESEARCH IN HIGH-THROUGHPUT BIOLOGY" in The Annals of Applied Statistics (2009, Vol. 3, No. 4, 1309–1334) which explains some of the background and investigative work they had to do to bring those mistakes to light. Best iain ----- Original Message ----- From: Bert Gunter <gunter.ber...@gene.com> To: r-help@r-project.org Cc: Sent: Monday, 26 March 2012, 19:12 Subject: [R] Completely Off Topic:Link to IOM report on use of "-omics" tests in clinical trials Warning: This has little directly to do with R, although R and related tools (e.g. sweave and other reproducible research tools) have a natural role to play. The IOM report: http://www.iom.edu/Reports/2012/Evolution-of-Translational-Omics.aspx that arose out of the Duke Univ. genomics testing scandal has been released. My thanks to Keith Baggerly for forwarding this. I believe that many R users in the medical research community will find this interesting, and I hope I do not venture too far out of line by passing on the link to readers of this list. It **will** have an important impact on so-called Personalized Health Care (which I guess affects all of us), and open source analytical (statistical) methodology is a central issue. For those interested, try the summary first. Best to all, Bert -- Bert Gunter Genentech Nonclinical Biostatistics Internal Contact Info: Phone: 467-7374 Website: http://pharmadevelopment.roche.com/index/pdb/pdb-functional-groups/pdb-biostatistics/pdb-ncb-home.htm ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code. ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.
