Hi, Marc,

Thank you very much for the reply. I'm using the gsDesign function to create an 
object of type gsDesign. But the inputs do not include the 'ratio' argument.

Dongli 

On Nov 14, 2011, at 5:50 PM, Marc Schwartz <marc_schwa...@me.com> wrote:

> On Nov 14, 2011, at 4:11 PM, Dongli Zhou wrote:
> 
>> I'm trying to use gsDesign for a noninferiority trial with binary
>> endpoint. Did anyone know how to specify the trial with different sample
>> sizes for two treatment groups? Thanks in advance!
> 
> 
> Hi,
> 
> Presuming that you are using the nBinomial() function, see the 'ratio' 
> argument, which defines the desired sample size ratio between the two groups.
> 
> See ?nBinomial and the examples there, which does include one using the 
> 'ratio' argument.
> 
> HTH,
> 
> Marc Schwartz
> 

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