On Nov 3, 2011, at 3:47 AM, David A. wrote:

> 
> Hi,
> 
> I am trying to estimate the sample size needed for the comparison of two 
> groups on a certain measurement, given some previous data at hand. I find 
> that the data collected does not follow a normal distribution, so I would 
> like to use a non-parametric option for sample size calculation.
> 
> I found the pwr package but I don't think it has this option and on the 
> internet found that http://www.epibiostat.ucsf.edu/biostat/sampsize.html says 
> only PASS allows non-parametric sample size calculations (although the 
> webpage is not updated).
> 
> Any help would be greatly appreciated
> 
> Thanks,
> 
> Dave


The first question is how "non normal" are your data? If you used some formal 
test for normality and the p value was <=0.05, I would suggest that you search 
the R-Help archives for a plethora of discussions on testing for normality. You 
will find that such tests should largely not be used in deference to the 
question "Are the data normal enough?". If they are or can be transformed 
reasonably, use standard functions for calculating power and sample size, such 
as power.t.test().

If you need to use a non-parametric test, you might want to review this page by 
Jerry Dallal:

  http://www.jerrydallal.com/LHSP/npar.htm

which has some general guidelines for calculating sample size predicated upon 
using standard parametric tests and then adjusting the sample size using the 
ARE (asymptotic relative efficiency) based upon the non-parametric intended.

HTH,

Marc Schwartz

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