... and additionally, 'ROC' from the Epi package does the second step
all in one.

Am 28.04.2011 13:01, schrieb Eik Vettorazzi:
> Hi Rasanga,
> you may have a look at the 'improveProb' function from the Hmisc
> package. There you can compare the increase in prognostic power for
> several combinations of markers. You can create a ROC curve for a
> combination of markers by using the predicted risks eg. from a logistic
> regression model.
> 
> To compare ROC curves of competing markers you can use 'roc.area.test'
> from the 'clinfun' package or 'hanley' from gcl.
> 
> hth.
> 
> 
> Am 27.04.2011 23:17, schrieb Rasanga Ruwanthi:
>> Dear list
>>  
>> I have 5 markers that can be used to detect an infection in combination. 
>> Could you please advise me how to use functions in ROCR/ other package to 
>> produce the ROC curve for a combination of markers?
>>  
>> I have used the following to get ROC statistics for each marker.
>> pred <- prediction(y$marker1, y$infectn)
>> perf <-performance(pred,"tpr","fpr")
>> plot(perf,ave="threshold",spread.estimate="boxplot")
>>
>> But I want know whether we could get this for more than one marker, so we 
>> can look at how good the markers in combination to predict the infection. 
>> I'm very grateful for any suggestion/help.
>>  
>> Thanks
>> Rasanga
>>  
>>
>>      [[alternative HTML version deleted]]
>>
>>
>>
>>
>> ______________________________________________
>> R-help@r-project.org mailing list
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>> PLEASE do read the posting guide http://www.R-project.org/posting-guide.html
>> and provide commented, minimal, self-contained, reproducible code.
> 

-- 
Eik Vettorazzi
Institut für Medizinische Biometrie und Epidemiologie
Universitätsklinikum Hamburg-Eppendorf

Martinistr. 52
20246 Hamburg

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