On Wed, 27 Apr 2011, peter dalgaard wrote:

On Apr 27, 2011, at 00:22 , Andre Guimaraes wrote:

Greetings from Rio de Janeiro, Brazil.

I am looking for advice / references on binary logistic regression
with weighted least squares (using lrm & weights), on the following
context:

1) unbalanced sample (n0=10000, n1=700);
2) sampling weights used to rebalance the sample (w0=1, w1=14.29); e
3) after modelling, adjust the intercept in order to reflect the
expected % of 1’s in the population (e.g., circa 7%, as opposed to
50%).

??

If the proportion of 1 in the population is about 7%, how exactly is the sample "unbalanced". I don't see a reason to use weights at all if the sample is representative of the population. The opposite situation, where the sample is balanced (e.g. case-control), the population not, and you are interested in the population values, _that_ might require weighting, with some care because case weighting and sample weighting are two different things so the s.e. will be wrong. That sort of stuff handled by the survey package.

However what you seem to be doing is to create results for an artificial 50/50 population, then project back to the population you were sampling from all along. I don't think this makes sense at all.

There are circumstances where it might. It is quite common in pattern recognition for the proportions in the training set to not reflect the population. And if the misclassification costs are asymmetric, you may want to weight the fit.

The case I encountered was SGA births. By definition there are about 10% 'successes', but false negatives are far more important than false positives (or one would simply predict all births as normal). This means that you want accurate estimation of probabilities in the right tail of the population distribution, and plug-in estimation of logistic regression is biased. One of many ways to reduce that bias is to re-weight the training set so the estimated probabilities of marginal cases are in the middle of the range.

Note that logistic regression is not normally fitted by 'weighted least squares' (not even by 'lrm' from some unstated package).

This is not a list for tutorials in advanced statistics, but one reference is my Pattern Recognition and Neural Networks book.


--
Peter Dalgaard
Center for Statistics, Copenhagen Business School
Solbjerg Plads 3, 2000 Frederiksberg, Denmark
Phone: (+45)38153501
Email: pd....@cbs.dk  Priv: pda...@gmail.com

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--
Brian D. Ripley,                  rip...@stats.ox.ac.uk
Professor of Applied Statistics,  http://www.stats.ox.ac.uk/~ripley/
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