> I was wondering why survreg (in survival package) can not handle > three-way interactions. I have an AFT .....
You have given us no data to diagnose your problem. What do you mean by "cannot handle" -- does the package print a message "no 3 way interactions", gives wrong answers, your laptop catches on fire when you run it, ....? Also, make sure you read help(frailty). The following is a key line "Use of gamma/ml or gaussian/reml with survreg does not lead to valid results." Terry Therneau ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.