Hallo, > fit12<-lmFit(qrg[,1:2]) > t12<-toptable(fit12,adjust="fdr",number=15000,genelist=qrg$genes[,1]) > t12 ID logFC t P.Value adj.P.Val B 1560 orf6.2714 -5,95911144 -7,504537362 0,0000000000000616459272630 0,0000000000430961073320568 20,85141454 8689 SW23 2,709344216 3,41198098 0,0006449261297639210000000 0,0396758555030764000000000 -0,62704052
The data example comes from one experiment, where I want to know if genes are differentially expressed. As I saw in the onlinehelp for toptable the value B is the log odds that the gene is differentially expressed. When I now look at the B value 20,85141454 it says that the gene orf6.2714 is in 20,85% differentially expressed. Is it right? But how should I interpret the second example SW23 with a negative B value? Can anyone discribe it to me in easy word? ;-) Thanks, Corinna [[alternative HTML version deleted]] ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.