Hello,
a) Thanks a lot for the answer relative to the dismissed coefficients.
However, the result below has been obtained in the R console and there
was no warning (please, see the full display below (***) if you wish).
"yi ~ X$V1 + X$V2 + X$V3 + X$V4 + X$V5 + X$V6 + X$V7 + X$V8 + X$V9 + X$V10"
Estimate Std. Error t value Pr(>|t|)
(Intercept) 0.018062134 5.624517e-17 3.211322e+14 0
X$V1 -0.011104627 3.084989e-17 -3.599567e+14 0
X$V2 -0.018536614 3.241635e-17 -5.718291e+14 0
X$V3 0.107341157 4.884358e-17 2.197651e+15 0
X$V4 0.003258493 3.286878e-17 9.913643e+13 0
X$V6 -0.051599957 4.203840e-17 -1.227448e+15 0
X$V8 -0.057207683 3.049835e-17 -1.875763e+15 0
X$V10 0.134643229 3.849911e-17 3.497308e+15 0
b) Would it be wise to check if the predictors are colinear, prior to
running the glm function ? How could it be performed, using the R language?
In additoon, in the present case, I would like to check for colinearity,
because I am puzzled by the absence of warning inthe R console.
c) I now answer the question relative to the very low std errors and the
way I generated the simulated data :
I ran the following code :
*****************
drawRegressionCoefficientsAndUpdateY <- function (target,
marks,
nbInd){
# X (individuals x marks)
# y (nbTargets x individuals)
l <- length(marks)
sigma <- runif(1,0.03,0.08)
# Values close to 0 are excluded from c0 simulation interval so that
the effect of the predictors are detectable.
c01 <- runif(1,-2,-0.5)
c02 <- runif(1,0.5,2)
i <- runif(1,1:2)
if (i==1) c0 <- c01 else c0 <- c02
coefficients <- c()
for(r in 1:l){
coefficient <- runif(1,0.2+sigma,1+sigma)
coefficients <- c(coefficients, coefficient)
}
// TILL THAT POINT, I RELIED ON THE PROCESS DESCRIBED IN A THESIS.
// THERE WAS NO INDICATION RELATIVE TO THE "ADJUSTMENT" OF EPSILON.
epsilon <- rnorm(1, mean = 0, sd = 0.002)
for (ind in 1:nbInd){
y[target,ind]<<- c0 + coefficients %*% X[ind,SNPs] + epsilon
}
Thank you in advance for your kind help.
C.S.
------------------------------------------------
------------------------------------------------
"yi ~ X$V1 + X$V2 + X$V3 + X$V4 + X$V5 + X$V6 + X$V7 + X$V8 + X$V9 + X$V10"
Estimate Std. Error t value Pr(>|t|)
(Intercept) 0.018062134 5.624517e-17 3.211322e+14 0
X$V1 -0.011104627 3.084989e-17 -3.599567e+14 0
X$V2 -0.018536614 3.241635e-17 -5.718291e+14 0
X$V3 0.107341157 4.884358e-17 2.197651e+15 0
X$V4 0.003258493 3.286878e-17 9.913643e+13 0
X$V6 -0.051599957 4.203840e-17 -1.227448e+15 0
X$V8 -0.057207683 3.049835e-17 -1.875763e+15 0
X$V10 0.134643229 3.849911e-17 3.497308e+15 0
I am sure to have regressed the right number of variables, since I check
that the formula is correct:
"yi ~ X$V1 + X$V2 + X$V3 + X$V4 + X$V5 + X$V6 + X$V7 + X$V8 + X$V9 + X$V10"
Could somebody explain to me
1) why there are mismatches between the "true" coefficients for
predictors 4 and 6
and
2) why there is no information edited for predictors 5, 7 and 9 ?
Thanks in advance for your kind help.
C.S.
------------------------------------------------
------------------------------------------------
(***)
Full console display ;
> inputoutputdir="/home/sinoquet/recherche/mcmc/output/sim_sat_02_10_10/"
> inputfilesnps="snps.txt"
> inputfilepheno="pheno.txt"
>
> X <<-
read.table(file=paste(inputoutputdir,inputfilesnps,sep=""),h=F) # data.frame
> #genotype file (individuals x SNPs); code: 0/1/2 : number of minor
alleles
>
> y <<-
read.table(file=paste(inputoutputdir,inputfilepheno,sep=""),h=F) #
data.frame
>
> #fit <- glm(yi ~ X$V1 + X$V2 + X$V3 + X$V4 + X$V5 + X$V6 + X$V7 +
X$V8 + X$V9 + X$V10, family = gaussian)
> #coefficients( summary(fit))
>
> #*****************************
> # BEGIN check real solution:
> target <- 1
> inputfilepredictors="predictor_descript.txt"
> f0 <- file(paste(inputoutputdir,inputfilepredictors,sep=""), open =
"r")
> # format of file f0:
> #target <predictors>
> #1 1 2 3 4 5 6 7 8 9 10
> line <- readLines(f0, n = 1) # header
> line <- readLines(f0, n = 1)
> v <- unlist(strsplit(line, split=" "))
> predictorsForThisTarget <- v[-1] # dismiss target number
> print(paste("!",v,"!",sep=" "))
[1] "! 1 !" "! 1 !" "! 2 !" "! 3 !" "! 4 !" "! 5 !" "! 6 !" "!
7 !"
[9] "! 8 !" "! 9 !" "! 10 !"
>
> nbPredictors <- length(predictorsForThisTarget)
> ch<-paste("X$V",predictorsForThisTarget[1],sep="")
> for (i in 2:nbPredictors){
+ item<-paste("X$V",predictorsForThisTarget[i],sep="")
+ ch<-paste(ch,item,sep=" + ")
+ }
>
> formulaString <- paste("yi",ch,sep=" ~ ")
> print(formulaString)
[1] "yi ~ X$V1 + X$V2 + X$V3 + X$V4 + X$V5 + X$V6 + X$V7 + X$V8 + X$V9 +
X$V10"
> formula <- as.formula(formulaString)
> yi <- unlist(y[target,])
> fit <- glm(formula, family = gaussian)
> print("*************BEGIN SOLUTION****************")
[1] "*************BEGIN SOLUTION****************"
> print(coefficients(summary(fit)))
Estimate Std. Error t value Pr(>|t|)
(Intercept) 0.018062134 5.624517e-17 3.211322e+14 0
X$V1 -0.011104627 3.084989e-17 -3.599567e+14 0
X$V2 -0.018536614 3.241635e-17 -5.718291e+14 0
X$V3 0.107341157 4.884358e-17 2.197651e+15 0
X$V4 0.003258493 3.286878e-17 9.913643e+13 0
X$V6 -0.051599957 4.203840e-17 -1.227448e+15 0
X$V8 -0.057207683 3.049835e-17 -1.875763e+15 0
X$V10 0.134643229 3.849911e-17 3.497308e+15 0
> print("*************END SOLUTION****************")
[1] "*************END SOLUTION****************"
> # END check real solution:
> #*****************************
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