Dear Michael If I understand you correctly, you already have an estimate of the measurement error? It would seem that if you can estimate the error, then this estimate comes with a standard error.
For example, suppose that you have a nonlinear model where one of the predictors is a sum of two variables, which has been measured with error. You then want to use simex to extrapolate the value the estimator of the nonlinear model would have if there were no error. If these two variables are related according to a factor model, then the measurement error estimate would be the correlation between the variables, with the corresponding s.e. (assuming the reliabilities of the variables are equal). It depends of course what the measurement model and corresponding estimates are but you usually get a standard error with the estimate. If you want to take into account the variability in this estimate, in the case of simex an approach would be to simulate values of the measurement error estimates from its distribution using the standard error, and repeat the simex procedure each time. You are then in the framework of multiple imputation. So you need to record the between- and within- variance and covariance of the estimates, and then combine them according to the rules laid out by Rubin to get the final variance of the nonlinear model's estimates. The between covariance matrix you get from the simulations. The within covariance matrix as I understood from the book needs to be bootstrapped. So it is quite a process but certainly possible! -daniel P.S. Note that simex is an approximate method; if you possibly can use them, the alternative likelihood based or estimating equations approaches provide a method of correcting the standard errors for uncertainty in the measurement error estimates. This is explained in the book by Carroll, Ruppert & Stefanski, in the appendix. On Jan 28, 2008 2:36 AM, Michael Kubovy <[EMAIL PROTECTED]> wrote: > Dear R-helpers, > > It is not clear to me how you get measurement.error SD when you have a > single dataset, and it is not clear to me how sensitive SIMEX is to > errors in the estimates of measurement error. > > Could someone please point me to the relevant literature? > _____________________________ > Professor Michael Kubovy > University of Virginia > Department of Psychology > USPS: P.O.Box 400400 Charlottesville, VA 22904-4400 > Parcels: Room 102 Gilmer Hall > McCormick Road Charlottesville, VA 22903 > Office: B011 +1-434-982-4729 > Lab: B019 +1-434-982-4751 > Fax: +1-434-982-4766 > WWW: > http://www.people.virginia.edu/~mk9y/<http://www.people.virginia.edu/%7Emk9y/> > > ______________________________________________ > R-help@r-project.org mailing list > https://stat.ethz.ch/mailman/listinfo/r-help > PLEASE do read the posting guide > http://www.R-project.org/posting-guide.html > and provide commented, minimal, self-contained, reproducible code. > [[alternative HTML version deleted]] ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.