On Tue, 10 Aug 2010, Carrie Li wrote:

Thank you both!

I found that the model with both x and y have measurement errors should be
pretty common in practice. But it seems to me that there is no a simple
solution for it...(I mean, a ready-to-use package or program handing this
model fitting problem. )

Hmm, have you actually looked at my reference? We provided a program in 1987.

One more question, is any reference that considers weighted measurement
error models (use the known variance of measurement errors as weights) ?

That's not really how you use known variances, which is the main case covered in our paper.

 
(I've search on google..got nothing...)

Thanks for your sharing opinions again! I appreciate!

Carrie--

On Tue, Aug 10, 2010 at 7:54 AM, Prof Brian Ripley <rip...@stats.ox.ac.uk>
wrote:
      On Tue, 10 Aug 2010, peter dalgaard wrote:


            On Aug 10, 2010, at 3:52 AM, Carrie Li wrote:

                  Thanks. I found the code in the link you
                  gave me very helpful.
                  But, I just have few questions regarding
                  the code.
                  It seems to me that in (from
                  wikipdeia)Deming regression, it assumes
                  that
                  the ratios of the variances of two
                  measurement errors are constant for all
                  pairs of (x_i, y_i). However, if the
                  ratios are not constant, (i.e. the
                  variances of measurement are
                  heterogeneous) , is it still appropriate
                  to use
                  Deming regression ?


            In a word, no.

            One way of looking at it is that as the ratio of
            variances varies from 0 to infinity, the analysis
            goes from regression of y on x to (inverse)
            regression of x on y, and those give different
            results, not just numerically but also
            asymptotically. I.e., getting the ratio wrong gives
            an inconsistent estimate; getting it wrong for some
            of the data, as is bound to happen if you assume it
            constant and it isn't, will also give a inconsistent
            estimate. Unless, that is, you can find a definition
            of "average ratio" that eliminates the bias, but I
            don't think it is worth the paperwork.

            Rather, I'd suggest direct minimization of the SSR
            (from the Wikipedia page), noting that you can plug
            in x_i^* as a function of beta also if the
            _individual_ ratios are known. (I get the feeling
            that someone must have been here before, so possibly
            others can fill in the gaps?) For modest sample
            sizes, it might also be possible to


Yes, people have been there before. Mike Thompson and I published a
now-much-cited-in-analytical-chemistry paper in The Analyst in 1987. A
companion paper was rejected by a mainstream statistics journal as
'already known', but the journal editor was unable to get any prior
publication out of the referee.

      formulate the problem as a nonlinear model and use nls().


Direct minimization is simple enough.


      --
      Peter Dalgaard
      Center for Statistics, Copenhagen Business School
      Solbjerg Plads 3, 2000 Frederiksberg, Denmark
      Phone: (+45)38153501
      Email: pd....@cbs.dk  Priv: pda...@gmail.com


--
Brian D. Ripley,                  rip...@stats.ox.ac.uk
Professor of Applied Statistics,  http://www.stats.ox.ac.uk/~ripley/
University of Oxford,             Tel:  +44 1865 272861 (self)
1 South Parks Road,                     +44 1865 272866 (PA)
Oxford OX1 3TG, UK                Fax:  +44 1865 272595





--
Brian D. Ripley,                  rip...@stats.ox.ac.uk
Professor of Applied Statistics,  http://www.stats.ox.ac.uk/~ripley/
University of Oxford,             Tel:  +44 1865 272861 (self)
1 South Parks Road,                     +44 1865 272866 (PA)
Oxford OX1 3TG, UK                Fax:  +44 1865 272595
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