Dear list, Has anyone created a version of SSmicmen that allows testing for group differences? The basic Michaelis-Menten equation is:
(Bmax * X) / (Kd + X). The nlme package allows modeling of random effects for Bmax and Kd as needed, but I curious how I can build in group differences? I have receptor binding data for strains of mice, and following Pinheiro and Bates' lead in their book, a random effort for animal differences in Bmax seems reasonable, within strain. However, I'd like a self-start function, or even just the equation above, modified to allow testing for strain differences in Bmax and or Kd. Thank you. -Dave ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.
