Hi Frank, Thank you for the correction, I don't work in clinical, so good you keep me honest. Nicholas On Sun, 11 Jan 2009 09:21:23 -0600, "Frank E Harrell Jr" <f.harr...@vanderbilt.edu> said: > Nicholas please note that FDA does not require type III sums of squares, > LOCF, and the use of any particular software. It is just the fact that > FDA does not disallow type III tests and LOCF that prevents pharma from > abandoning these terrible methods. > > Frank > -- > Frank E Harrell Jr Professor and Chair School of Medicine > Department of Biostatistics Vanderbilt University
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