Seattle, November 20, 2022

 Hello again, morphmetters,

       Jim's comment about the "traffic policeman" approach
 to mosquito wing vein landmarking echoes many
 older discussions in foundations of measurement.  The best place
 for that "policeman" is the center of the largest circle that
 can be inscribed inside the boldface Helvetica Y-shape where the
 veins are seen to branch.  (This would be the triple-point
 of the medial axis of that outline, see my 1991 textbook,
 Section 3.5.)  Such an operational definition is fine as long
 as the data are imagined as curving lines of infinitesimal
 thickness  -- the original article on medial axes (Blum 1963)
 argues that the human visual system actually carries out this
 sort of optimization all by itself.  But the approach fails
 completely under higher magnification, when these "curves" turn out
 instead to be curving cliffs of gray-scale, for which the
 location of "the" line is a matter of image gradients
 (second derivatives). As the
 information in grayscale images is isomorphic to
 curving surfaces in 3D space, the same critique applies to
 actual surface data as well. This is an example of a point the
 Dutch physicist Jan Koenderink made in his great treatise
 "Solid Shape" (MIT Press, 1990), where he says that inspection
 of EVERY observation that uses a machine requires
 attention to two crucial parameters, the outer scale of
 that machine's spectrum and its inner scale.  Our visual systems
 do this automatically, or, to use Bessel's own term,
 "involuntarily," more's the pity -- in the Mach band process,
 we see edges where there aren't any, only gradients.

      Which brings up another fundamental point, the difference
 between observations based on first-order derivatives with respect
 to time or space and observations based on  derivatives
 of second order or higher.
 (There's a nice comment on this distinction in Wigner's great
 essay "The Unreasonable Effectiveness of Mathematics in the
 Natural Sciences," 1960.)  The Hoffmann article I cited in my
 previous email notes that Bessel measured the time of transit
 of a star across the zenith by setting a grid of evenly spaced
 lines in his telescope, starting a metronome nearby, and
 visualizing the location of the star with respect to the
 line at the two consecutive click times of which one just preceded
 the crossing, the other coming just after. The corresponding
 time measurement might be precise to about a tenth of a second,
 Hoffmann claims, given what we know about the human perceptome.
 But this is a _linear_ phenomenon, the crossing of a line --the
 first derivative is nonzero.  Compare it to any of the usual
 definitions of landmarks in the textbooks or the journals, which
 refer to second derivatives (extremes of position of
 a curve with respect to some coordinate axis, or tangents to a curve)
 or even third derivatives (extremes of curvature, as at Glabella).
 Orbitale, the "bottom" of the outline of the optic socket, is
 a particularly notorious example of this ambiguity; another is
 the once-standard "Frankfurt Horizontal" for registration of
 skulls in comparative studies, as it is defined
 by a line tangent to two separate "curves" that are actually
 oblique cliffs in space, one contact "point" at Orbitale and the other
 at the auditory meatus. (If you don't see the problem, just
 pick up an actual skull with one hand while you hold a ruler
 with the other.)  I got my start in craniofacial biology
 over forty years ago in a paper with Robert Moyers on the meaninglessness
 of the Frankfurt Horizontal ("The Inappropriateness of
 Conventional Cephalometrics," 1979), but the problem had been
 acknowledged for decades before _that._

       This apercu, in turn, echoes an old claim of the psychologist
 Edwin Boring (1886-1968), quoted in the Hoffmann article I cited
 yesterday, who claimed (back in the era when biometrics dealt
 with continuous measures rather than discrete genomes) that
 that field reduced to psychometrics, not vice versa.  His
 argument (a polemic, really), which you can find in Harry Woolf's
 proceeding "Quantification" of 1961, makes fascinating reading today.
 Particularly relevant are two of his "generalities":

       (.) "A new line of investigation is established and
 everyone joins in the new pursuit." And,

       (.) "Quantification is favored by the desire of investigators
 to claim the prestige of science for their research."

 And he concludes,

       "So opinion -- sometimes within scientific awareness, sometimes
 in spite of scientific unawareness, operates to aid or hinder
 progress, and you may not know which it is, any more than you know
 at the moment whether progress has got itself into a blind alley or
 is going straight with a clear course ahead. And that is the
 way that quantification in science comes about, is pushed ahead or
 held back ..."

        I recommend Woolf's book warmly to any of you who might
 have some interest in history of science.
 For instance, it includes the first appearance in print
 of Thomas Kuhn's argument about "paradigms" that turned into
 the all-time best seller in philosophy of science, his
 "Structure of Scientific Revolutions."  And please forgive these
 occasional lectures of mine on history of science, especially
 their prevailing theme of the irony that "everything
 important was already said before, but nobody
 listened" -- they are so much fun to write!

                             Fred Bookstein


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