On Wednesday, June 15, 1994 8:17:40 PM UTC-4, "Glenn Cantor" wrote:
> I have transfected cells with a plasmid containing a hygromycin 
> selectable marker.  To compare transfection efficiency in various 
> cell lines, I would like to compare the amounts of hygromycin 
> phosphotransferase which the lines express.  Does anyone know if 
> antibodies or an antibody-based kit are available for detection of 
> hygromycin phosphotransferase?  (5'-3' has an ELISA for detection of 
> neomycin phosphotransferase II, but doesn't have one for hygromycin.)
> 
> Thanks!
> 
> Debra Hoover

Can someone provide a reference regarding spontaneous mutation of CHO-K1 
(untransfected) to become hygromycin B resistant? Is there data on the IC50 of 
hygromycin B on untransfected CHO-K1?
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