Hi,
I am having some trouble with miRNA expression. I have not worked with
miRNAs before. Can someone tell me how the 5p and 3p arms work with respect
to a specific cell line? I know we can either have a mature 3p miRNA or a
5p miRNA. But how does it work when I over express miRNA using a plasmid?
Can the over expression plasmid be targeted towards a specific mature
sequence (3p or 5p)?

Thanks in advance.

Sindhu.
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