Switched to Linux Mint for unrelated reasons and noticed that the bug is gone.
Linux Mint Cinnamon 21.1 with kernel 5.15.0-56-generic.
Chances are that the bug is resolved in mainstream Ubuntu as well. Will check 
when I find the time.

$dmesg | grep -i tpm
[    0.000000] efi: SMBIOS=0xd6e24000 ACPI=0xd7ffd000 ACPI 2.0=0xd7ffd014 
ESRT=0xd6cb3000 MOKvar=0xd0735000 RNG=0xd6cb4a98 TPMEventLog=0xc9c7e018 
[    0.000000] TPM Final Events table not present
[    0.022627] ACPI: SSDT 0x00000000D7FFA000 0004B7 (v02 LENOVO Tpm2Tabl 
00001000 INTL 20141107)
[    0.022639] ACPI: TPM2 0x00000000D7FF8000 000034 (v03 LENOVO TP-R02   
00001490 PTEC 00000002)
[    0.022779] ACPI: Reserving TPM2 table memory at [mem 0xd7ff8000-0xd7ff8033]

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https://bugs.launchpad.net/bugs/1971567

Title:
  TPM breaks resume from suspend

Status in linux package in Ubuntu:
  Confirmed

Bug description:
  After upgrading Lenovo Thinkpad X260 from 21.10 to 22.04, following
  error shows at boot:

  [    4.830657] tpm tpm0: Operation Timed out
  [   11.654699] tpm tpm0: Operation Timed out
  [   11.654718] tpm_crb: probe of MSFT0101:00 failed with error -62

  Notable consequence is that the laptop will not resume from suspend
  any more, even with the power button pressed.

  After disabling TPM ("Security Chip" in Lenovo BIOS) completely,
  everything works normal.

  ProblemType: Bug
  DistroRelease: Ubuntu 22.04
  Package: linux-image-5.15.0-27-generic 5.15.0-27.28
  ProcVersionSignature: Ubuntu 5.15.0-27.28-generic 5.15.30
  Uname: Linux 5.15.0-27-generic x86_64
  ApportVersion: 2.20.11-0ubuntu82
  Architecture: amd64
  AudioDevicesInUse:
   USER        PID ACCESS COMMAND
   /dev/snd/controlC0:  martin     2147 F.... pulseaudio
  CasperMD5CheckResult: pass
  CurrentDesktop: ubuntu:GNOME
  Date: Wed May  4 13:15:17 2022
  InstallationDate: Installed on 2022-03-06 (59 days ago)
  InstallationMedia: Ubuntu 21.10 "Impish Indri" - Release amd64 (20211012)
  MachineType: LENOVO 20F5S0V400
  ProcEnviron:
   TERM=xterm-256color
   PATH=(custom, no user)
   XDG_RUNTIME_DIR=<set>
   LANG=de_DE.UTF-8
   SHELL=/bin/bash
  ProcFB: 0 i915drmfb
  ProcKernelCmdLine: BOOT_IMAGE=/vmlinuz-5.15.0-27-generic 
root=/dev/mapper/vgubuntu-root ro quiet splash vt.handoff=7
  RelatedPackageVersions:
   linux-restricted-modules-5.15.0-27-generic N/A
   linux-backports-modules-5.15.0-27-generic  N/A
   linux-firmware                             20220329.git681281e4-0ubuntu1
  SourcePackage: linux
  UpgradeStatus: Upgraded to jammy on 2022-04-24 (10 days ago)
  dmi.bios.date: 02/23/2022
  dmi.bios.release: 1.49
  dmi.bios.vendor: LENOVO
  dmi.bios.version: R02ET76W (1.49 )
  dmi.board.asset.tag: Not Available
  dmi.board.name: 20F5S0V400
  dmi.board.vendor: LENOVO
  dmi.board.version: SDK0J40697 WIN
  dmi.chassis.asset.tag: No Asset Information
  dmi.chassis.type: 10
  dmi.chassis.vendor: LENOVO
  dmi.chassis.version: None
  dmi.ec.firmware.release: 1.16
  dmi.modalias: 
dmi:bvnLENOVO:bvrR02ET76W(1.49):bd02/23/2022:br1.49:efr1.16:svnLENOVO:pn20F5S0V400:pvrThinkPadX260:rvnLENOVO:rn20F5S0V400:rvrSDK0J40697WIN:cvnLENOVO:ct10:cvrNone:skuLENOVO_MT_20F5_BU_Think_FM_ThinkPadX260:
  dmi.product.family: ThinkPad X260
  dmi.product.name: 20F5S0V400
  dmi.product.sku: LENOVO_MT_20F5_BU_Think_FM_ThinkPad X260
  dmi.product.version: ThinkPad X260
  dmi.sys.vendor: LENOVO

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