The School of Life and Health Science of Aston University has opened a funded 
PhD position in applied Neuroscience

Topic:
Many patients with epileptic seizures are proven medically resistant and 
respective surgery is the only remaining treatment alternative. This is 
performed for removing a small portion of brain tissue that is currently 
defined using intracranial electroencephalogram (iEEG). To date, this results 
in a significant number of patients continuing to experience postsurgical 
seizures. During the last few years, high-frequency oscillations (HFOs above 80 
Hz) have emerged as a new promising biomarker in pre-surgical diagnosis of 
epileptogenicity, while the resection of the tissue generating HFOs improves 
surgical outcome in patients with medically refractory epilepsy (MRE). The 
ultimate goal of the project is to automatically detect HFOs and localise their 
source of origin, by using only high-density EEG and/or MEG, which is necessary 
for a solid sampling and accurate localisation of HFOs on the scalp. The main 
outcomes of the project will be so, the gained knowledge for the mechanism of 
HFOs and their relation to epilepsy as a valuable tool for the clinicians who 
perform surgical operations, and patients who will refrain from invasive 
monitoring (iEEG).  

Candidate: 

The successful candidate will contribute to the development and testing of 
algorithms able to automatically detect HFOs. They will be working on the 
boarders of biomedical engineering and human neuroscience. This is a unique 
opportunity, since you will have the chance to work inside a multidisciplinary 
project funded by the EU, and visit project partners to gain more research 
knowledge and experience.  

Aston University:
Aston University was ranked 5th out of 94 UK Higher Education Institutions for 
research in Allied Health Professions (REF 2014) and was ranked 1st for 
research environment. Additional information about research in the School can 
be found at http://www.aston.ac.uk/lhs/research/. Informal enquiries can be 
made to Dr Manousos Klados: [email protected].

Financial Support:
The studentship is open to Home/EU students only and comprises of a tax-free 
stipend at the 2018/19 RCUK rate of £14,777 p.a. and payment of Home/EU tuition 
fees only. The studentship is available for three years, subject to 
satisfactory progress review at the end of the first year, with a registration 
of July 2019.

Application Requirements: 
- Eligible Applicants should hold at least a Bachelor (Hons.) Degree of either 
1st Class/ 2.1 or MSc/MRes in a relevant subject.
- EU Applicants will need to demonstrate adequate proficiency in English 
Language skills, with a minimum overall score of 93 (Internet Based) (with a 
minimum score in each section of: R: 18, W: 23, L: 19 and S: 19) in TOEFL or 
IELTS with minimum marks of 6.0 in each section and an overall band of 6.5. 

More information you can find at: 
https://jobs.aston.ac.uk/Vacancy.aspx?ref=R190113



Best Regards
Manos
 
Manousos A. Klados, MSc, PhD, FIMA, FHEA
Lecturer in Biomedical Engineering
Coordinator of HOPE funded under H2020-MSCA-RISE
Department of Biomedical Engineering
School of Life & Health Sciences, Aston University
Phone: +44(0)1212043740
Email: [email protected] 
Websites: http://www.mklados.com <http://www.mklados.com/> & 
http://www.aston.ac.uk/lhs/staff/az-index/mklados
Address: MB555 – Aston Triangle, B47ET, Birmingham, UK



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