> Yes. Output to ps and then use psbook and pstops. psbook page specifications are very flexible, but need a bit of mental activity to get the positioning right. Here's what I usually use for A4 paper (21 cm x 29.7 cm):
psbook | pstops -pa4 '4:0L@.7071(21cm,0cm)+1L@.7071(21cm,14.85cm),2R@.7071(0cm,29.7cm)+3R@.7071(0cm,14.85cm)' This already does the tumble, so you must print in "normal" duplex mode (long side flip). If you have a Postscript printer, you can also use sed to automatically insert a << /Duplex true >> setpagedevice into the output stream, if that's not your default already. You need to adapt the scaling factor "@sss" and the positioning on the final page "(xxx,yyy)" to your paper size (coordinate origin in Postscript is the lower left-hand corner). If you use non-1:sqrt(2) aspect ratio paper, you may also need to reformat your original output to have the aspect ratio of half of the final output page.
