https://gcc.gnu.org/bugzilla/show_bug.cgi?id=119607
--- Comment #9 from Jakub Jelinek <jakub at gcc dot gnu.org> --- It seems g_closure_ref is inlined into 3 different functions, g_closure_invalidate g_closure_invoke _g_closure_invoke_va and those aren't further inlined. So the noipa attribute presumably just stops inlining that. So, can you try to add __attribute__((optimize (0))) to each of those 3 instead of noinline attribute on g_closure_ref and see which of those 3 works and which don't? Ideally so that we have just one problematic function to look at rather than 3...