https://gcc.gnu.org/bugzilla/show_bug.cgi?id=106053
--- Comment #2 from Richard Biener <rguenth at gcc dot gnu.org> --- It works with -mavx or when 'foo' is early inlined (using always-inline). Working: u.1_8 = u; _9 = (long long unsigned int) u.1_8; u64_0_10 = _9 | 23725760132; _18 = u64_0_10 * 3095179400; _50 = _18 == 0; _53 = (__int128) _50; _54 = -_53; _58 = (__int128) _50; _59 = -_58; D.2295.a = { 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 }; _69 = BIT_FIELD_REF <D.2295.b[0], 128, 128>; _66 = BIT_FIELD_REF <D.2295.b[0], 128, 0>; _67 = VIEW_CONVERT_EXPR<vector(4) unsigned int>(_54); _68 = _66 + _67; _70 = VIEW_CONVERT_EXPR<vector(4) unsigned int>(_59); _71 = _69 + _70; v256u8_r_26 = {_68, _71}; x = v256u8_r_26; not working: u.1_27 = u; _28 = (long long unsigned int) u.1_27; u64_0_29 = _28 | 23725760132; _38 = u64_0_29 * 3095179400; _56 = _38 == 0; _59 = (__int128) _56; _60 = -_59; D.2034.a = { 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 }; _70 = BIT_FIELD_REF <D.2034.b[0], 128, 128>; _67 = BIT_FIELD_REF <D.2034.b[0], 128, 0>; _69 = _67 + { 4294967295, 4294967295, 4294967295, 4294967295 }; _71 = VIEW_CONVERT_EXPR<vector(4) unsigned int>(_60); _72 = _70 + _71; BIT_FIELD_REF <x, 128, 0> = _69; BIT_FIELD_REF <x, 128, 128> = _72; and CCP produces the bogus constant folded vector from _38 = u64_0_29 * 3095179400; _1 = (<signed-boolean:128>) _38; _50 = _1 ^ 1; _53 = _50 & 1; _54 = (__int128) _53; _55 = -_54; _68 = VIEW_CONVERT_EXPR<vector(4) unsigned int>(_55); _69 = _68 + _67; but it's interpretations are OK I think. It must go wrong in veclower somehow, the broken version ends up with a compare in signed-bool while the working one uses an __int128 compare.